Mouse Monoclonal Antibody to Acetyl-p53 (Lys382)

包装: 1G|100G|500G|1KG|100KG

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别名:Cellular tumor antigen p53; Cys 51 stop; Tp53; Tumor protein p53
应用:IHC
反应种属:Human,Rat,Mouse
规格：50μl/100μl

Description
Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains.

Description

Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains.

Specification
Aliases	Cellular tumor antigen p53; Cys 51 stop; Tp53; Tumor protein p53
Entrez GeneID	7157
Swissprot	P04637
clone	12D4
Host/Isotype	Mouse IgG1
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Rat,Mouse
Immunogen	Synthetic peptide conjugated to KLH.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Application
IHC	1/50-1/100

	Immunohistochemistry analysis of paraffin-embedded Human Colon Carcinoma Tissue using Acetyl-p53 (Lys382) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
	Immunohistochemical analysis of paraffin-embedded Human tonsils using Acetyl-p53 (Lys382) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.