Mouse Monoclonal Antibody to AKR1C1

包装: 1G|100G|500G|1KG|100KG

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别名:C9;DD1;DDH;DDH1;H-37;HBAB;MBAB;HAKRC;DD1/DD2;2-ALPHA-HSD;20-ALPHA-HSD
应用:WB,IHC,FCM
反应种属:Human,Mouse,Rabbit
规格：50μl/100μl

Description
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008]

Description

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008]

Specification
Aliases	C9;DD1;DDH;DDH1;H-37;HBAB;MBAB;HAKRC;DD1/DD2;2-ALPHA-HSD;20-ALPHA-HSD
Entrez GeneID	1645
Swissprot	Q04828
clone	6D6F6
WB Predicted band size	36.7kDa
Host/Isotype	Mouse IgG1
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rabbit
Formulation	Purified antibody in PBS with 0.05% sodium azide

Application
WB	1/500-1/1000
IHC	1/200-1/400
FCM	1/200 – 1/400

	Western blot analysis using AKRAC1 mouse mAb against HepG2(1) mouse liver(2)cell lysate.
	Flow cytometric analysis of Hela cells using AKR1C1 mouse mAb (green) and negative control (red).
	Immunohistochemical analysis of paraffin-embedded human lung cancer tissues using AKR1C1 mouse mAb with DAB stainin.
	Immunohistochemical analysis of paraffin-embedded human stomach cancer tissues using AKR1C1 mouse mAb with DAB stainin.
	Immunohistochemical analysis of paraffin-embedded human rrectal cancer tissues using AKR1C1 mouse mAb with DAB stainin.
	Immunohistochemical analysis of paraffin-embedded mouse liver tissues using AKR1C1 mouse mAb with DAB staining.
	Immunohistochemical analysis of paraffin-embedded rabbit liver tissues using AKR1C1 mouse mAb with DAB staining.
	Immunohistochemical analysis of paraffin-embedded rabbit small intestine tissues using AKR1C1 mouse mAb with DAB staining.