Mouse Monoclonal Antibody to AKR1C1

包装: 1G|100G|500G|1KG|100KG

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别名:C9;DD1;DDH;DDH1;H-37;HBAB;MBAB;HAKRC;DD1/DD2;2-ALPHA-HSD;20-ALPHA-HSD
应用:WB,IHC,FCM
反应种属:Human,Rabbit
规格：50μl/100μl

Description
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008]

Description

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008]

Specification
Aliases	C9;DD1;DDH;DDH1;H-37;HBAB;MBAB;HAKRC;DD1/DD2;2-ALPHA-HSD;20-ALPHA-HSD
Entrez GeneID	1645
Swissprot	Q04828
clone	8C12B11
WB Predicted band size	36.8kDa
Host/Isotype	Mouse IgG1
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Rabbit
Formulation	Purified antibody in PBS with 0.05% sodium azide

Application
WB	1/500-1/1000
IHC	1/200-1/400
FCM	1/200 – 1/400

	Western blot analysis using AKRAC1 mouse mAb against Hela(1),HepG2(2)cell lysate.
	Flow cytometric analysis of Hela cells using AKR1C1 mouse mAb (green) and negative control (red).
	Immunohistochemical analysis of paraffin-embedded human lung cancer tissues using AKR1C1 mouse mAb with DAB staining.
	Immunohistochemical analysis of paraffin-embedded human gastric cancer tissues using AKR1C1 mouse mAb with DAB staining.
	Immunohistochemical analysis of paraffin-embedded rabbit liver tissues using AKR1C1 mouse mAb with DAB staining.
	Immunohistochemical analysis of paraffin-embedded small intestine tissues using AKR1C1 mouse mAb with DAB staining.