Mouse Monoclonal Antibody to CD10

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别名:MME; EPN; Neprilysin; Atriopeptidase; Common acute lymphocytic leukemia antigen; CALLA; Enkephalinase; Neutral endopeptidase 24.11; NEP; Neutral endopeptidase; Skin fibroblast elastase; SFE; CD10
应用:IHC
反应种属:Human,Rat,Mouse
规格：50μl/100μl

Description
CD10 is a transmembrane type II molecule and functions as a metallo-peptidase requiring zinc. Specifically, CD10 cleaves 1-3 amino-terminal amino acids from peptides with a preference for neutral amino acids (valine, iso-leucine, phenylalanine, leucine or alanine). Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.

Description

CD10 is a transmembrane type II molecule and functions as a metallo-peptidase requiring zinc. Specifically, CD10 cleaves 1-3 amino-terminal amino acids from peptides with a preference for neutral amino acids (valine, iso-leucine, phenylalanine, leucine or alanine). Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.

Specification
Aliases	MME; EPN; Neprilysin; Atriopeptidase; Common acute lymphocytic leukemia antigen; CALLA; Enkephalinase; Neutral endopeptidase 24.11; NEP; Neutral endopeptidase; Skin fibroblast elastase; SFE; CD10
Entrez GeneID	4311
Swissprot	P08473
clone	6F7
Host/Isotype	Mouse IgG1
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Rat,Mouse
Immunogen	Synthetic peptide conjugated to KLH.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Application
IHC	1/50-1/100

	Immunofluorescence analysis of CD10 in Human uterus tissue using CD10 antibody(red),and DAPI (blue).
	Immunofluorescence analysis of CD10 in rat kidney using CD10 antibody(red),and DAPI (blue).
	Immunohistochemistry analysis of paraffin-embedded Human uterus tissue using CD10 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Negative control was used by secondary antibody only.
	Immunohistochemistry analysis of paraffin-embedded mouse lung tissue using CD10 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.Negative control was used by secondary antibody only.
	Immunohistochemistry analysis of paraffin-embedded Human breast cancer using CD10 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.v
	Immunohistochemistry analysis of paraffin-embedded rat kidney tissue using CD10 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Negative control was used by secondary antibody only.