Mouse Monoclonal Antibody to CD133

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别名:Prominin-1; Antigen AC133; Prominin-like protein 1; CD133.
应用:WB
反应种属:Human
规格：50μl/100μl

Description
This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.

Description

This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.

Specification
Aliases	Prominin-1; Antigen AC133; Prominin-like protein 1; CD133.
Entrez GeneID	8842
Swissprot	O43490
clone	6H5
WB Predicted band size	Calculated MW: 97 kDa; Observed MW: 133 kDa
Host/Isotype	Mouse IgG2a
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant human Prominin-1 protein fragments expressed in E.coli.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Application
WB	1/500-1/1000

	Western blot analysis of CD133 in CaCo2 lysates using CD133 antibody.
	Western blot analysis of CD133 in CHO-K1 cells nontransfected (A) or transfected (B) with CD133 using CD133 antibody.