Mouse Monoclonal Antibody to CD31

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别名:Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; GPIIA’; PECA1; CD antigen CD31
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
PECAM-1 a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues.

Description

PECAM-1 a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues.

Specification
Aliases	Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; GPIIA’; PECA1; CD antigen CD31
Entrez GeneID	5175
Swissprot	P16284
clone	5C12
WB Predicted band size	Calculated MW: 83 kDa; Observed MW: 130 kDa
Host/Isotype	Mouse IgG1
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant human CD31 protein fragments expressed in E.coli.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Application
WB	1/500-1/1000
IHC	1/50-1/100

	Western blot analysis of CD31 in THP-1 lysates using CD31 antibody.
	Immunohistochemistry analysis of paraffin-embedded Human tonsils using CD31/PECAM1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.