Mouse Monoclonal Antibody to CD45

包装: 1G|100G|500G|1KG|100KG

现货支持定制

QQ咨询
| 微信咨询

400-880-2824

满200元免运费
正品保障提供发票
现货闪电当时发货

别名:GP180; L CA; CD45 antigen
应用:WB,IHC,ICC
反应种属:Human
规格：50μl/100μl

Description
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN . Dephosphorylates LYN, and thereby modulates LYN activity.

Description

Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN . Dephosphorylates LYN, and thereby modulates LYN activity.

Specification
Aliases	GP180; L CA; CD45 antigen
Entrez GeneID	19264
Swissprot	P06800
clone	9D3
WB Predicted band size	Calculated MW: 145 kDa; Observed MW: 145 kDa
Host/Isotype	Mouse IgG1
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthetic Peptide of CD45
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Application
WB	1/500-1/1000
IHC	1/50-1/100
ICC	1/50-1/200

	Western blot analysis of CD45 in Jurkat lysates using CD45 antibody.
	Immunofluorescence analysis of CD45 in Human livercancer tissue using CD45 antibody(red),and DAPI (blue).
	Immunohistochemical analysis of paraffin-embedded Human tonsils using CD45 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.Negative control was used by secondary antibody only.