Mouse Monoclonal Antibody to Cleaved-Caspase 8

包装: 1G|100G|500G|1KG|100KG

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别名:CASP8; MCH5; Caspase-8; CASP-8; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACH
应用:WB,IHC,ICC
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit.

Specification
Aliases	CASP8; MCH5; Caspase-8; CASP-8; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACH
Entrez GeneID	841
Swissprot	Q14790
WB Predicted band size	Calculated MW: 55 kDa; Observed MW: 43,57 kDa
Host/Isotype	Mouse IgG1
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Recombinant Protein of Caspase-8
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Application
WB	1/500-1/1000
IHC	1/50-1/100
ICC	1/50-1/200

	Western blot analysis of Caspase8 in K562, 3T3, MCF-7 and Jurkat lysates using Caspase8 antibody.
	Western blot analysis of Caspase 8 (2G12) in THP-1, rat Brain, Hela lysates using Caspase8 antibody.
	Western blot analysis of Caspase 8 (2G12) in Jurkat, MOLT4 lysates using Caspase 8 (2G12) antibody
	Immunocytochemistry analysis of Caspase8 (green) in Hela using Caspase8 antibody,and DAPI(blue).
	Immunohistochemistry analysis of paraffin-embedded mouse Spleen Tissue using Caspase8 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.