Mouse Monoclonal Antibody to EGFR

包装: 1G|100G|500G|1KG|100KG

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别名:EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
应用:WB,ICC,IP
反应种属:Human,Monkey
规格：50μl/100μl

Description
EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation.

Description

EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation.

Specification
Aliases	EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
Entrez GeneID	1956
Swissprot	P00533
clone	7B11
WB Predicted band size	Calculated MW: 134 kDa; Observed MW: 175 kDa
Host/Isotype	Mouse IgG1
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Monkey
Immunogen	Purified recombinant human EGFR protein fragments expressed in E.coli.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Application
IP	1/20
WB	1/500-1/1000
ICC	1/50-1/200

	Western blot analysis of EGFR in A549 and COS7 lysates using EGFR antibody.
	Western blot analysis of EGFR in A549 and MDA-MB-468 lysates using EGFR antibody.
	Immunoprecipitation analysis of EGFR in Hela lysates using EGFR antibody.
	Immunocytochemistry analysis of EGFR in HeLa using EGFR antibody.
	Immunocytochemistry analysis of EGFR in MDA-MB-468 cells using EGFR antibody.