中文 
别名:Eukaryotic translation initiation factor 2-alpha kinase 3, 2.7.11.1, PRKR-like endoplasmic reticulum kinase, Pancreatic eIF2-alpha kinase, HsPEK, EIF2AK3, PEK, PERK应用:WB
反应种属:Human, Mouse, Rat
规格：50μl/100μl
| Description |
|---|
| Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin-D1 (CCND1). Involved in control of mitochondrial morphology and function (By similarity). |
| Specification | |
|---|---|
| Aliases | Eukaryotic translation initiation factor 2-alpha kinase 3, 2.7.11.1, PRKR-like endoplasmic reticulum kinase, Pancreatic eIF2-alpha kinase, HsPEK, EIF2AK3, PEK, PERK |
| Entrez GeneID | 9451 |
| Swissprot | Q9NZJ5 |
| WB Predicted band size | 125.2kDa |
| Host/Isotype | Mouse IgG1 |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | This EIF2AK3 antibody is generated from a mouse immunized with a recombinant protein conjugated synthetic peptide between 530-850 amino acids from human EIF2AK3. |
| Application | |
|---|---|
| WB | 1/250-1/1000 |
 |
All lanes : Anti-EIF2AK3 Antibody at 1:250-1:1000 dilution Lane 1: A549 whole cell lysate Lane 2: PC-12 whole cell lysate Lane 3: mouse brain lysate Lane 4: mouse liver lysate Lysates/proteins at 20 µg per lane. Secondary Predicted band size : 125 kDa Blocking/Dilution buffer: 5% NFDM/TBST. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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