别名:ERCC1; DNA excision repair protein ERCC-1应用:WB
反应种属:Human
规格:50μl/100μl
| Description |
|---|
| DNA repair systems operate in all living cells to manage a variety of DNA lesions. Nucleotide excision repair (NER) is implemented in cases where bulky helix-distorting lesions occur, such as those brought about by UV and certain chemicals. Research studies have shown that expression of ERCC1 is related to survival rate and response to chemotherapeutic drugs in several human cancers including non-small cell lung cancer (NSCLC). |
| Specification | |
|---|---|
| Aliases | ERCC1; DNA excision repair protein ERCC-1 |
| Entrez GeneID | 2067 |
| Swissprot | P07992 |
| clone | 10H6 |
| WB Predicted band size | Calculated MW: 33 kDa; Observed MW: 39 kDa |
| Host/Isotype | Mouse IgG2b |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant human ERCC1 protein fragments expressed in E.coli. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Application | |
|---|---|
| WB | 1/500-1/1000 |
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Western blot analysis of ERCC1 in T47D, ZR751, CaCO2 and Molt4 lysates using ERCC1 antibody. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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