别名:Peptidyl-prolyl cis-trans isomerase FKBP1A, PPIase FKBP1A, 5.2.1.8, 12 kDa FK506-binding protein, 12 kDa FKBP, FKBP-12, Calstabin-1, FK506-binding protein 1A, FKBP-1A, Immunophilin FKBP12, Rotamase, FKBP1A, FKBP1, FKBP12应用:WB
反应种属:Human, Mouse, Rat
规格:50μl/100μl
Description |
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Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruits SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. |
Specification | |
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Aliases | Peptidyl-prolyl cis-trans isomerase FKBP1A, PPIase FKBP1A, 5.2.1.8, 12 kDa FK506-binding protein, 12 kDa FKBP, FKBP-12, Calstabin-1, FK506-binding protein 1A, FKBP-1A, Immunophilin FKBP12, Rotamase, FKBP1A, FKBP1, FKBP12 |
Entrez GeneID | 2280 |
Swissprot | P62942 |
WB Predicted band size | 12.0kDa |
Host/Isotype | Mouse IgG1 |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | This antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between amino acids from human. |
Application | |
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WB | 1/4000 |
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All lanes : Anti-FKBP1A at 1:4000 dilution Lane 1: Jurkat whole cell lysate Lane 2: MCF-7 whole cell lysate Lane 3: Mouse brain whole tissue lysate Lane 4: Rat brain whole tissue lysate Lysates/proteins at 20 µg per lane. Secondary Predicted band size : 12 kDa Blocking/Dilution buffer: 5% NFDM/TBST. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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