别名:GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B应用:WB,ICC,FCM,IP
反应种属:Human,Mouse,Rat
规格:50μl/100μl
| Description |
|---|
| Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase .GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation.In skeletal muscle, it contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. |
| Specification | |
|---|---|
| Aliases | GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B |
| Entrez GeneID | 2932 |
| Swissprot | P49841 |
| clone | 12B5 |
| WB Predicted band size | Calculated MW: 47 kDa; Observed MW: 47 kDa |
| Host/Isotype | Mouse IgG2a |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Purified recombinant GSK-3β protein fragments expressed in E.coli. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Application | |
|---|---|
| IP | 1/20 |
| WB | 1/500-1/1000 |
| ICC | 1/50-1/200 |
| FCM | 1/50-1/100 |
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Western blot analysis of GSK3 beta in A549, Hela, 3T3 and rat Brain lysates using GSK3 beta antibody. |
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Immunoprecipitation analysis of GSK3 beta in Hela lysates using GSK3 beta antibody.western blot analysis of GSK3 beta using GSK3 beta antibody. |
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Immunocytochemistry analysis of GSK3 beta in HeLa using GSK3 beta antibody. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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