中文 
别名:HDAC3; Histone deacetylase 3; HD3; RPD3-2; SMAP45应用:WB
反应种属:Human,Mouse,Rat
规格：50μl/100μl
| Description |
|---|
| HDAC3 is a nuclear and cytoplasmic protein that deacetylates both histone (H2A, H3, H4) and non-histone substrates (RelA, SRY, p53, MEF2, PCAF and p300/CBP). HDAC3 deacetylase activity is stimulated by interactions with the N-CoR and SMRT co-repressor proteins. Together, these three proteins form a functional complex that represses transcription associated with nuclear hormone receptors and other transcription factors, including Rev-Erb, COUP-TF, DAX1, MAD and Pit-1. |
| Specification | |
|---|---|
| Aliases | HDAC3; Histone deacetylase 3; HD3; RPD3-2; SMAP45 |
| Entrez GeneID | 8841 |
| Swissprot | O15379 |
| clone | 8B10 |
| WB Predicted band size | Calculated MW: 49 kDa; Observed MW: 49 kDa |
| Host/Isotype | Mouse IgG1 |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Purified recombinant human HDAC3 protein fragments expressed in E.coli. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Application | |
|---|---|
| WB | 1/500-1/1000 |
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Western blot analysis of HDAC3 in THP-1, LNCAP, MCF-7, PC-12, 293, Jurkat, 3T3 and Hela lysates using HDAC3 antibody. |
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Western blot analysis of HDAC3 in Jurkat and Hela lysates using HDAC3 antibody. |
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Western blot analysis of HDAC3 in HDAC3 knock dowm 293T, wildtype (WT), K562, Jurkat and Hela lysates using HDAC3 antibody. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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