别名:Prostate-specific antigen, PSA, Gamma-seminoprotein, Seminin, Kallikrein-3, P-30 antigen, Semenogelase, KLK3, APS应用:WB
反应种属:Human
规格:50μl/100μl
| Description |
|---|
| Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. |
| Specification | |
|---|---|
| Aliases | Prostate-specific antigen, PSA, Gamma-seminoprotein, Seminin, Kallikrein-3, P-30 antigen, Semenogelase, KLK3, APS |
| Entrez GeneID | 354 |
| Swissprot | P07288 |
| WB Predicted band size | 28.7kDa |
| Host/Isotype | Mouse IgM |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This HKLK3 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 220-250 amino acids from human HKLK3. |
| Formulation | Mouse monoclonal antibody supplied in crude ascites with 0.05% sodium azide. |
| Application | |
|---|---|
| WB | 1/500-1/1600 |
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HKLK3 Antibody (C234) (Cat. #P32007) western blot analysis in A549 cell line lysates (35μg/lane).This demonstrates the HKLK3 antibody detected the HKLK3 protein (arrow). |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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