别名:Histamine N-methyltransferase, HMT, HNMT应用:WB
反应种属:Human
规格:50μl/100μl
| Description |
|---|
| In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. |
| Specification | |
|---|---|
| Aliases | Histamine N-methyltransferase, HMT, HNMT |
| Entrez GeneID | 3176 |
| Swissprot | P50135 |
| WB Predicted band size | 33.3kDa |
| Host/Isotype | Mouse IgG1 |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified His-tagged HNMT protein(Fragment) was used to produced this monoclonal antibody. |
| Formulation | Mouse monoclonal antibody supplied in crude ascites with 0.05% sodium azide. |
| Application | |
|---|---|
| WB | 1/100-1/8000 |
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HNMT Antibody (Cat. #P31696) western blot analysis in HepG2 cell line lysates (35μg/lane).This demonstrates the HNMT antibody detected the HNMT protein (arrow). |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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