Mouse Monoclonal Antibody to Hsp70 1A

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别名:HSP72; HSPA1; HSP70I; HSPA1B; HSP70-1; HSP70-1A.
应用:WB,IHC,ICC
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.

Description

In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.

Specification
Aliases	HSP72; HSPA1; HSP70I; HSPA1B; HSP70-1; HSP70-1A.
Entrez GeneID	3303
Swissprot	P0DMV8
clone	8G9
WB Predicted band size	Calculated MW: 70 kDa; Observed MW: 70 kDa
Host/Isotype	Mouse IgG1
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic Peptide of HSP70
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Application
WB	1/500-1/1000
IHC	1/50-1/100
ICC	1/50-1/200

	Western blot analysis of Hsp70 in MCF-7 and Hela lysates using Hsp70 antibody.
	Western blot analysis of Hsp70 1A in Hela, mouse Brain lysates using Hsp70 1A antibody.
	Western blot analysis of Hsp70 1A in A549, K562, Hela lysates using Hsp70 1A antibody
	Immunofluorescence analysis of Hsp70 1A in Hela using Hsp70 1A antibody(left) ,and DAPI (blue).
	Immunohistochemistry analysis of paraffin-embedded Human tonsil tissue using HSP70 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.