中文 
别名:Ig delta chain C region, IGHD应用:WB
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| IgD is the major antigen receptor isotype on the surface of most peripheral B-cells, where it is coexpressed with IgM. The membrane-bound IgD (mIgD) induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. Soluble IgD (sIgD) concentration in serum below those of IgG, IgA, and IgM but much higher than that of IgE. IgM and IgD molecules present on B cells have identical V regions and antigen-binding sites. After the antigen binds to the B-cell receptor, the secreted form sIgD is shut off. IgD is a potent inducer of TNF, IL1B, and IL1RN. IgD also induces release of IL6, IL10, and LIF from peripheral blood mononuclear cells. Monocytes seem to be the main producers of cytokines in vitro in the presence of IgD. |
| Specification | |
|---|---|
| Aliases | Ig delta chain C region, IGHD |
| Swissprot | P01880 |
| WB Predicted band size | 42.3kDa |
| Host/Isotype | Mouse IgM |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This IGHD antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 37-64 amino acids from the N-terminal region of human IGHD. |
| Formulation | Purified monoclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS. |
| Application | |
|---|---|
| WB | 1/100-1/250 |
 |
IGHD Antibody (N-term)(Cat. #P32257) western blot analysis in CEM cell line lysates (35μg/lane).This demonstrates the IGHD antibody detected the IGHD protein (arrow). |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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