Mouse Monoclonal Antibody to IL6

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别名:CDF;HGF;HSF;BSF2;IL-6;BSF-2;IFNB2;IFN-beta-2
应用:IHC,FCM
反应种属:Human,Mouse,Rat,Rabbit
规格：50μl/100μl

Description
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19

Description

This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19

Specification
Aliases	CDF;HGF;HSF;BSF2;IL-6;BSF-2;IFNB2;IFN-beta-2
Entrez GeneID	3569
Swissprot	P05231
clone	7C10C6
WB Predicted band size	23.7kDa
Host/Isotype	Mouse IgG2b
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat,Rabbit
Formulation	Purified antibody in PBS with 0.05% sodium azide

Application
IHC	1/200-1/400
FCM	1/200 – 1/400

	Flow cytometric analysis of Hela cells using IL6 mouse mAb (green) and negative control (red).
	Immunohistochemical analysis of paraffin-embedded human liver cancer tissues using IL6 mouse mAb with DAB staining.
	Immunohistochemical analysis of paraffin-embedded human liver tissues using IL6 mouse mAb with DAB staining.
	Immunohistochemical analysis of paraffin-embeddedrat rat kidney tissues using IL6 mouse mAb with DAB staining.
	Immunohistochemical analysis of paraffin-embeddedrat mouse kidney tissues using IL6 mouse mAb with DAB staining.
	Immunohistochemical analysis of paraffin-embeddedrat rabbit kidney tissues using IL6 mouse mAb with DAB staining.