Mouse Monoclonal Antibody to MAFK

包装: 1G|100G|500G|1KG|100KG

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别名:Transcription factor MafK, Erythroid transcription factor NF-E2 p18 subunit, MAFK
应用:WB,FCM
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor.

Description

Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor.

Specification
Aliases	Transcription factor MafK, Erythroid transcription factor NF-E2 p18 subunit, MAFK
Entrez GeneID	7975
Swissprot	O60675
WB Predicted band size	17.5kDa
Host/Isotype	Mouse IgG1
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	This MAFK antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between amino acids from the human region of human MAFK.

Application
WB	1/1000
FCM	1/25

	Western blot analysis of lysate from Jurkat cell line, using MAFK Antibody(Cat. #P32590). P32590 was diluted at 1:1000. A goat anti-mouse IgG H&L(HRP) at 1:3000 dilution was used as the secondary antibody. Lysate at 35μg.
	Flow cytometric analysis of Hela cells using MAFK Antibody(green, Cat#P32590) compared to an isotype control of mouse IgG1(blue). P32590 was diluted at 1:25 dilution. An Alexa Fluor® 488 goat anti-mouse lgG at 1:400 dilution was used as the secondary antibody.