Mouse Monoclonal Antibody to MMP2

包装: 1G|100G|500G|1KG|100KG

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别名:MMP2; CLG4A; 72 kDa type IV collagenase; 72 kDa gelatinase; Gelatinase A; Matrix metalloproteinase-2; MMP-2; TBE-1
应用:WB,ICC
反应种属:Human,Mouse
规格：50μl/100μl

Description
MMP2 Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-\|-Leu bond. Appears to have a role in myocardial cell death pathways.

Description

MMP2 Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways.

Specification
Aliases	MMP2; CLG4A; 72 kDa type IV collagenase; 72 kDa gelatinase; Gelatinase A; Matrix metalloproteinase-2; MMP-2; TBE-1
Entrez GeneID	4313
Swissprot	P08253
clone	3C8
WB Predicted band size	Calculated MW: 74 kDa; Observed MW: 74 kDa
Host/Isotype	Mouse IgG1
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Purified recombinant human MMP-2 protein expressed in E.coli.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Application
WB	1/500-1/1000
ICC	1/50-1/200

	Western blot analysis of MMP2 in CHO-K1 (B) and CHO-K1 transfected by MMP2 fragment(A) lysates using MMP2 antibody.
	Western blot analysis of MMP2 in Raw264.7 lysates using MMP2 antibody.
	Immunofluorescence analysis of MMP2 in Hela using MMP2 antibody,and DAPI (blue).