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瑞威尔生物科技 REVERE

Mouse Monoclonal Antibody to PARP1

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别名:PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1
应用:WB,IHC
反应种属:Human,Mouse,Rat
规格:50μl/100μl

Description
Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Specification
Aliases PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1
Entrez GeneID 142
Swissprot P09874
clone 5C2
WB Predicted band size Calculated MW: 113 kDa; Observed MW: 116 kDa
Host/Isotype Mouse IgG1
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen Synthetic Peptide of Cleaved PARP
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Application
WB 1/500-1/1000
IHC 1/50-1/100

Western blot analysis of PARP1 in Hela, MCF-7 and Jurkat lysates using PARP antibody.
Western blot analysis of PARP1 in K562, Ramos, Jurkat lysates using PARP (1C2) antibody.
Western blot analysis of PARP1 in 3T3, Hela lysates using PARP1 antibody
Immunohistochemistry analysis of paraffin-embedded Human Tonsil Tissue using Cleaved PARP antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。