别名:PKM; OIP3; PK2; PK3; PKM2; Pyruvate kinase isozymes M1/M2; Cytosolic thyroid hormone-binding protein; CTHBP; Opa-interacting protein 3; OIP-3; Pyruvate kinase 2/3; Pyruvate kinase muscle isozyme; Thyroid hormone-binding protein 1; THBP1; Tu应用:WB,ICC,IP
反应种属:Human,Mouse,Monkey
规格:50μl/100μl
| Description |
|---|
| Pyruvate kinase is a glycolytic enzyme that catalyses the conversion of phosphoenolpyruvate to pyruvate. PKM2 is shown to be essential for aerobic glycolysis in tumors, known as the Warburg effect. |
| Specification | |
|---|---|
| Aliases | PKM; OIP3; PK2; PK3; PKM2; Pyruvate kinase isozymes M1/M2; Cytosolic thyroid hormone-binding protein; CTHBP; Opa-interacting protein 3; OIP-3; Pyruvate kinase 2/3; Pyruvate kinase muscle isozyme; Thyroid hormone-binding protein 1; THBP1; Tu |
| Entrez GeneID | 5315 |
| Swissprot | P14618 |
| clone | 1H2 |
| WB Predicted band size | Calculated MW: 58 kDa; Observed MW: 58 kDa |
| Host/Isotype | Mouse IgG2b |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Monkey |
| Immunogen | Purified recombinant human PKM2 protein fragments expressed in E.coli. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.02% sodium azide, pH 7.4. |
| Application | |
|---|---|
| IP | 1/20 |
| WB | 1/500-1/1000 |
| ICC | 1/50-1/200 |
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Western blot analysis of PKM2 in HCT116, COS7, K562, A549 and Hela lysates using PKM2 antibody. |
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Immunoprecipitation analysis of PKM2 in Hela lysates using PKM2 antibody. |
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Immunofluorescence analysis of PKM2 in 3T3 using PKM2 antibody. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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