Mouse Monoclonal Antibody to Rad9

包装: 1G|100G|500G|1KG|100KG

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别名:RAD9; hRAD9
应用:WB,IP
反应种属:Human,Mouse,Rat,Monkey
规格：50μl/100μl

Description
This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3′ to 5′ exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Description

This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3′ to 5′ exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specification
Aliases	RAD9; hRAD9
Entrez GeneID	5883
Swissprot	Q99638
WB Predicted band size	Calculated MW: 43 kDa; Observed MW: 60 kDa
Host/Isotype	Mouse IgG2b
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat,Monkey
Immunogen	Purified recombinant human RAD9A protein fragments expressed in E.coli
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Application
IP	1/20
WB	1/500-1/1000

	Western blot analysis of RAD9A in Hela, MCF-7, 3T3, COS7 and rat testis lysates using RAD9A antibody.
	Immunoprecipitation analysis of Rad9 in Hela and 3T3 lysates using RAD9A antibody.