Mouse Monoclonal Antibody to RCC1

包装: 1G|100G|500G|1KG|100KG

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别名:Regulator of chromosome condensation, Cell cycle regulatory protein, Chromosome condensation protein 1, RCC1, CHC1
应用:WB
反应种属:Human, Mouse
规格：50μl/100μl

Description
Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.

Description

Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.

Specification
Aliases	Regulator of chromosome condensation, Cell cycle regulatory protein, Chromosome condensation protein 1, RCC1, CHC1
Entrez GeneID	1104
Swissprot	P18754
WB Predicted band size	45.0kDa
Host/Isotype	Mouse IgG1
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	This RCC1 monoclonal antibody is generated from mouse immunized with RCC1 recombinant protein.
Formulation	Mouse monoclonal antibody supplied in crude ascites with 0.05% sodium azide.

Application
WB	1/2000

All lanes : Anti-RCC1 Antibody at 1:2000 dilution
Lane 1: HL-60 whole cell lysate
Lane 2: Hela whole cell lysate
Lane 3: U-251MG whole cell lysate
Lane 4: MCF-7 whole cell lysate
Lane 5: Mouse heart lysate

Lysates/proteins at 20 µg per lane.

Secondary
Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.

Predicted band size : 45 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.

本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。

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