中文 
别名:Receptor-interacting serine/threonine-protein kinase 3, 2.7.11.1, RIP-like protein kinase 3, Receptor-interacting protein 3, RIP-3, RIPK3, RIP3应用:WB
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production. |
| Specification | |
|---|---|
| Aliases | Receptor-interacting serine/threonine-protein kinase 3, 2.7.11.1, RIP-like protein kinase 3, Receptor-interacting protein 3, RIP-3, RIPK3, RIP3 |
| Entrez GeneID | 11035 |
| Swissprot | Q9Y572 |
| WB Predicted band size | 56.9kDa |
| Host/Isotype | Mouse IgG1 |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This RIPK3 antibody is generated from a mouse immunized with a recombinate protein from the human region of human RIPK3. |
| Application | |
|---|---|
| WB | 1/1000 |
 |
All lanes : Anti-RIPK3 Antibody at 1:1000 dilution Lane 1: HT-29 whole cell lysate Lane 2: Jurkat whole cell lysate Lane 3: SW620 whole cell lysate Lane 4: THP-1 whole cell lysate Lane 5: K562 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Predicted band size : 57 kDa Blocking/Dilution buffer: 5% NFDM/TBST. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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