Mouse Monoclonal Antibody to SIRT2

包装: 1G|100G|500G|1KG|100KG

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别名:SIRT2; SIR2L; SIR2L2; NAD-dependent protein deacetylase sirtuin-2; Regulatory protein SIR2 homolog 2; SIR2-like protein 2
应用:WB,ICC
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
Participate in a variety of cellular functions, including histone deacetylation, gene silencing, chromosomal stability, and aging. SIRT2, a human homolog of the yeast SIR2, functions as transcriptional silencing mediator at mating-type loci, telomeres and ribosomal gene clusters. SIRT2 expression increases dramatically during mitosis and is multiply phosphorylated at the G(2)/M transition of the cell cycle.

Description

Participate in a variety of cellular functions, including histone deacetylation, gene silencing, chromosomal stability, and aging. SIRT2, a human homolog of the yeast SIR2, functions as transcriptional silencing mediator at mating-type loci, telomeres and ribosomal gene clusters. SIRT2 expression increases dramatically during mitosis and is multiply phosphorylated at the G(2)/M transition of the cell cycle.

Specification
Aliases	SIRT2; SIR2L; SIR2L2; NAD-dependent protein deacetylase sirtuin-2; Regulatory protein SIR2 homolog 2; SIR2-like protein 2
Entrez GeneID	22933
Swissprot	Q8IXJ6
clone	1G7
WB Predicted band size	Calculated MW: 43 kDa; Observed MW: 43 kDa
Host/Isotype	Mouse IgG2b
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Purified recombinant human SirT2 protein expressed in E.coli.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Application
WB	1/500-1/1000
ICC	1/50-1/200

	Western blot analysis of SirT2 in PC-12, rat Brain and mouse Brain lysates using SirT2 antibody.
	Western blot analysis of SIRT2 in rat Cerebral Cortex and rat Brain lysates using SirT2 antibody.
	Immunofluorescence analysis of SIRT2 in Hela using SirT2 antibody(green) and Histone H3.1 (Phospho-Ser10) (310045) antibody(red).