中文 
别名:ZAP70; SRK; Tyrosine-protein kinase ZAP-70; 70 kDa zeta-chain associated protein; Syk-related tyrosine kinase应用:WB,IP
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| The Syk family protein tyrosine kinase Zap-70 is expressed in T and NK cells and plays a critical role in mediating T cell activation in response to T cell receptor (TCR) engagement. Following TCR engagement, Zap-70 is rapidly phosphorylated on several tyrosine residues through autophosphorylation and transphosphorylation by the Src family tyrosine kinase Lck. |
| Specification | |
|---|---|
| Aliases | ZAP70; SRK; Tyrosine-protein kinase ZAP-70; 70 kDa zeta-chain associated protein; Syk-related tyrosine kinase |
| Entrez GeneID | 7535 |
| Swissprot | P43403 |
| clone | 7A2 |
| WB Predicted band size | Calculated MW: 70 kDa; Observed MW: 70 kDa |
| Host/Isotype | Mouse IgG2b |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant human ZAP-70 protein fragments expressed in E.coli. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Application | |
|---|---|
| IP | 1/20 |
| WB | 1/500-1/1000 |
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Western blot analysis of ZAP70 in CEM and Jurkat lysates, negative in the Ramos lysates using ZAP70 antibody. |
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Immunoprecipitation analysis of ZAP70 in Jurkat lysates (ZAP70 positive expression cell line)and Ramos lysates(ZAP70 negative expression cell line) using ZAP70 antibody. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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