Rabbit Monoclonal Antibody to Adiponectin

包装: 1G|100G|500G|1KG|100KG

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别名:Ad; APN; Acdc; Adid; apM1; 30kDa; GBP28; adipo; Acrp30
应用:WB,IHC,ICC
反应种属:Mouse,Rat
规格：50μl/100μl

Description
Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.

Description

Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.

Specification
Aliases	Ad; APN; Acdc; Adid; apM1; 30kDa; GBP28; adipo; Acrp30
Entrez GeneID	11450
Swissprot	Q60994
WB Predicted band size	Calculated MW: 27 kDa; Observed MW: 30 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Mouse,Rat
Immunogen	Recombinant protein of mouse Adiponectin
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Application
WB	1/500-1/1000
IHC	1/50-1/100
ICC	1/50-1/200

	Western blot analysis of Adiponectin in rat fat lysates using Adiponectin antibody.
	Western blot analysis of Adiponectin in 3T3-L1 lysates using Adiponectin antibody.