别名:MLLT10; AF10; Protein AF-10; ALL1-fused gene from chromosome 10 protein应用:WB,IHC
反应种属:Human
规格:50μl/100μl
| Description |
|---|
| Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA. In cells, binding to unmodified histone H3 regulates DOT1L functions including histone H3 ‘Lys-79’ dimethylation (H3K79me2) and gene activation (PubMed:26439302). |
| Specification | |
|---|---|
| Aliases | MLLT10; AF10; Protein AF-10; ALL1-fused gene from chromosome 10 protein |
| Entrez GeneID | 8028 |
| Swissprot | P55197 |
| WB Predicted band size | Calculated MW: 113 kDa; Observed MW: 140 kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Recombinant protein of human AF10 |
| Formulation | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Application | |
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
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Western blot analysis of AF10 in Hela, K562 lysates using AF10 antibody. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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