Rabbit Monoclonal Antibody to Angiotensin Converting Enzyme 1

包装: 1G|100G|500G|1KG|100KG

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别名:ACE; Dipeptidyl carboxypeptidase I; Kininase II
应用:WB,IHC
反应种属:Mouse,Rat
规格：50μl/100μl

Description
Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. This GPIase activity seems to be crucial for the egg-binding ability of the sperm.

Description

Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. This GPIase activity seems to be crucial for the egg-binding ability of the sperm.

Specification
Aliases	ACE; Dipeptidyl carboxypeptidase I; Kininase II
Entrez GeneID	11421
Swissprot	P09470
WB Predicted band size	Calculated MW: 151 kDa; Observed MW: 180 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Mouse,Rat
Immunogen	Recombinant protein of mouse Angiotensin Converting Enzyme 1
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Application
WB	1/500-1/1000
IHC	1/50-1/100

	Western blot analysis of Angiotensin Converting Enzyme 1 in rat liver lysates using Angiotensin Converting Enzyme 1 antibody.
	Western blot analysis of Angiotensin Converting Enzyme 1 in mouse liver, mouse heart lysates using Angiotensin Converting Enzyme 1 antibody.