中文 
别名:AOA; AOA1; AXA1; EAOH; EOAHA; FHA-HIT应用:WB,ICC
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair (PubMed:15380105, PubMed:15044383, PubMed:16964241, PubMed:17276982, PubMed:24362567). Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species (PubMed:16964241, PubMed:24362567). Catalyzes the release of adenylate groups covalently linked to 5′-phosphate termini, resulting in the production of 5′-phosphate termini that can be efficiently rejoined (PubMed:16964241, PubMed:17276982, PubMed:24362567). Also able to hydrolyze adenosine 5′-monophosphoramidate (AMP-NH2) and diadenosine tetraphosphate (AppppA), but with lower catalytic activity (PubMed:16547001). Likewise, catalyzes the release of 3′-linked guanosine (DNAppG) and inosine (DNAppI) from DNA, but has higher specific activity with 5′-linked adenosine (AppDNA) . |
| Specification | |
|---|---|
| Aliases | AOA; AOA1; AXA1; EAOH; EOAHA; FHA-HIT |
| Entrez GeneID | 54840 |
| Swissprot | Q7Z2E3 |
| WB Predicted band size | Calculated MW: 41 kDa; Observed MW: 41 kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthetic peptide of human Aprataxin |
| Formulation | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Application | |
|---|---|
| WB | 1/500-1/1000 |
| ICC | 1/50-1/200 |
 |
Western blot analysis of Aprataxin in K562, Hela lysates using Aprataxin antibody. |
 |
Immunocytochemistry analysis of Aprataxin (green) in U87-MG using Aprataxin antibody,and DAPI(blue). |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
暂无评论
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
发表回复