别名:Ago 2; Argonaute 2; dAgo2; eIF2C 2; hAgo2; PPD应用:WB
反应种属:Human,Rat
规格:50μl/100μl
Description |
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Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). Can also upregulate the translation of specific mRNAs under certain growth conditions. Binds to the AU element of the 3′-UTR of the TNF (TNF-alpha) mRNA and upregulates translation under conditions of serum starvation. Also required for transcriptional gene silencing (TGS), in which short RNAs known as antigene RNAs or agRNAs direct the transcriptional repression of complementary promoter regions. |
Specification | |
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Aliases | Ago 2; Argonaute 2; dAgo2; eIF2C 2; hAgo2; PPD |
Entrez GeneID | 27161 |
Swissprot | Q9UKV8 |
WB Predicted band size | Calculated MW: 97 kDa; Observed MW: 97 kDa |
Host/Isotype | Rabbit IgG |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Rat |
Immunogen | A synthetic peptide of human Argonaute-2 |
Formulation | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
Application | |
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WB | 1/500-1/1000 |
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Western blot analysis of Argonaute2 in PC-3 lysates using Argonaute 2 antibody. |
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Western blot analysis of Argonaute2 in C6 lysates using Argonaute2 antibody. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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