中文 
别名:ATM; Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated应用:WB,IP
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. |
| Specification | |
|---|---|
| Aliases | ATM; Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated |
| Entrez GeneID | 472 |
| Swissprot | Q13315 |
| WB Predicted band size | Calculated MW: 351 kDa; Observed MW: 351 kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Recombinant protein of ATM |
| Formulation | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Application | |
|---|---|
| IP | 1/20 |
| WB | 1/500-1/1000 |
 |
Western blot analysis of ATM in Hela lysates using ATM antibody. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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