别名:ACLY; ATP-citrate synthase; ATP-citrate; pro-S-)-lyase; ACL; Citrate cleavage enzyme应用:WB,ICC,IP
反应种属:Human,Mouse,Rat
规格:50μl/100μl
Description |
---|
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. |
Specification | |
---|---|
Aliases | ACLY; ATP-citrate synthase; ATP-citrate; pro-S-)-lyase; ACL; Citrate cleavage enzyme |
Entrez GeneID | 47 |
Swissprot | P53396 |
WB Predicted band size | Calculated MW: 121 kDa; Observed MW: 121 kDa |
Host/Isotype | Rabbit IgG |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | A synthetic peptide of human ATP citrate lyase |
Formulation | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
Application | |
---|---|
IP | 1/20 |
WB | 1/500-1/1000 |
ICC | 1/50-1/200 |
![]() |
Western blot analysis of ATP citrate lyase in K562, C6, 3T3, Hela lysates using ATP citrate lyase antibody. |
![]() |
Immunocytochemistry analysis of ATP Citrate lyase (green) in A549 using ATP Citrate lyase antibody,and DAPI(blue). |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
暂无评论
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
发表回复