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瑞威尔生物科技 REVERE

Rabbit Monoclonal Antibody to ATP6V1A

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别名:HO68; VA68; VPP2; Vma1; ARCL2D; ATP6A1; IECEE3; ATP6V1A1
应用:WB,IHC,IP
反应种属:Human,Mouse,Rat
规格:50μl/100μl

Description
Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe2+ prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633). May play a role in neurite development and synaptic connectivity (PubMed:29668857).
Specification
Aliases HO68; VA68; VPP2; Vma1; ARCL2D; ATP6A1; IECEE3; ATP6V1A1
Entrez GeneID 523
Swissprot P38606
WB Predicted band size Calculated MW: 68 kDa; Observed MW: 68 kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human ATP6V1A
Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Application
IP 1/20
WB 1/500-1/1000
IHC 1/50-1/100

Western blot analysis of ATP6V1A in K562, rat Brain, 3T3 lysates using ATP6V1A antibody.
Immunohistochemistry analysis of paraffin-embedded Human tonsil using ATP6V1A antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。