Rabbit Monoclonal Antibody to BRAT1

包装: 1G|100G|500G|1KG|100KG

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别名:BRCA1-associated ATM activator 1; BRCA1-associated protein required for ATM activation protein 1
应用:WB,IP
反应种属:Human
规格：50μl/100μl

Description
Involved in DNA damage response; activates kinases ATM, SMC1A and PRKDC by modulating their phosphorylation status following ionizing radiation (IR) stress (PubMed:16452482, PubMed:22977523). Plays a role in regulating mitochondrial function and cell proliferation (PubMed:25070371). Required for protein stability of MTOR and MTOR-related proteins, and cell cycle progress by growth factors (PubMed:25657994).

Description

Involved in DNA damage response; activates kinases ATM, SMC1A and PRKDC by modulating their phosphorylation status following ionizing radiation (IR) stress (PubMed:16452482, PubMed:22977523). Plays a role in regulating mitochondrial function and cell proliferation (PubMed:25070371). Required for protein stability of MTOR and MTOR-related proteins, and cell cycle progress by growth factors (PubMed:25657994).

Specification
Aliases	BRCA1-associated ATM activator 1; BRCA1-associated protein required for ATM activation protein 1
Entrez GeneID	221927
Swissprot	Q6PJG6
WB Predicted band size	Calculated MW: 88 kDa; Observed MW: 88 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Recombinant protein of human BRAT1
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA