Rabbit Monoclonal Antibody to BTF3

包装: 1G|100G|500G|1KG|100KG

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别名:NACB; BTF3a; BTF3b; BETA-NAC
应用:WB,IHC,IP
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
When associated with NACA, prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. BTF3 is also a general transcription factor that can form a stable complex with RNA polymerase II. Required for the initiation of transcription.

Description

When associated with NACA, prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. BTF3 is also a general transcription factor that can form a stable complex with RNA polymerase II. Required for the initiation of transcription.

Specification
Aliases	NACB; BTF3a; BTF3b; BETA-NAC
Entrez GeneID	689
Swissprot	P20290
WB Predicted band size	Calculated MW: 22 kDa; Observed MW: 22 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Recombinant protein of human BTF3
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Application
IP	1/20
WB	1/500-1/1000
IHC	1/50-1/100

	Western blot analysis of BTF3 in C6, 3T3 lysates using BTF3 antibody.
	Immunohistochemistry analysis of paraffin-embedded Human breast cancer using BTF3 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.