Rabbit Monoclonal Antibody to Caspase 6

包装: 1G|100G|500G|1KG|100KG

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别名:CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2
应用:WB
反应种属:Human,Rat
规格：50μl/100μl

Description
Caspase-6 (Mch2) is one of the major executioner caspases functioning in cellular apoptotic processes. Upon apoptotic stimulation, initiator caspases such as caspase-9 are cleaved and activated. The activated upstream caspases further process downstream executioner caspases, such as caspase-3 and caspase-6, by cleaving them into large and small subunits, thereby initiating a caspase cascade leading to apoptosis. One of the major targets for caspase-6 is the membrane associated protein lamin A.

Description

Caspase-6 (Mch2) is one of the major executioner caspases functioning in cellular apoptotic processes. Upon apoptotic stimulation, initiator caspases such as caspase-9 are cleaved and activated. The activated upstream caspases further process downstream executioner caspases, such as caspase-3 and caspase-6, by cleaving them into large and small subunits, thereby initiating a caspase cascade leading to apoptosis. One of the major targets for caspase-6 is the membrane associated protein lamin A.

Specification
Aliases	CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2
Entrez GeneID	839
Swissprot	P55212
WB Predicted band size	Calculated MW: 33 kDa; Observed MW: 11,33 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Rat
Immunogen	Recombinant protein of human Caspase-6
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA