Rabbit Monoclonal Antibody to Caveolin 1

包装: 1G|100G|500G|1KG|100KG

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别名:CAV1; CAV; Caveolin-1
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
Caveolin-1 may act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.

Description

Caveolin-1 may act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.

Specification
Aliases	CAV1; CAV; Caveolin-1
Entrez GeneID	857
Swissprot	Q03135
WB Predicted band size	Calculated MW: 20 kDa; Observed MW: 20 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	A synthetic peptide of human Caveolin-1
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Application
WB	1/500-1/1000
IHC	1/50-1/100

	Western blot analysis of Caveolin1 in Hela lysates using Caveolin 1 antibody.
	Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Caveolin1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.