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瑞威尔生物科技 REVERE

Rabbit Monoclonal Antibody to Chk2

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别名:CHEK2; CDS1; CHK2; RAD53; Serine/threonine-protein kinase Chk2; CHK2 checkpoint homolog; Cds1 homolog; Hucds1; hCds1; Checkpoint kinase 2
应用:WB,ICC,IP
反应种属:Human
规格:50μl/100μl

Description
These are known to be preferred sites for phosphorylation by ATM/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function.
Specification
Aliases CHEK2; CDS1; CHK2; RAD53; Serine/threonine-protein kinase Chk2; CHK2 checkpoint homolog; Cds1 homolog; Hucds1; hCds1; Checkpoint kinase 2
Entrez GeneID 11200
Swissprot O96017
WB Predicted band size Calculated MW: 61 kDa; Observed MW: 61 kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Recombinant protein of human Chk2
Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Application
IP 1/20
WB 1/500-1/1000
ICC 1/50-1/200

Western blot analysis of Chk2 in Jurkat lysates using Chk2 antibody.
Immunocytochemistry analysis of Chk2 (green) in HCT116 using Chk2 antibody,and DAPI(blue).

本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。