Rabbit Monoclonal Antibody to CIRBP

包装: 1G|100G|500G|1KG|100KG

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别名:CIRP
应用:WB,IHC,IP
反应种属:Human
规格：50μl/100μl

Description
Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3′-untranslated regions (3′-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor . Promotes assembly of stress granules (SGs), when overexpressed.

Description

Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3′-untranslated regions (3′-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor . Promotes assembly of stress granules (SGs), when overexpressed.

Specification
Aliases	CIRP
Entrez GeneID	1153
Swissprot	Q14011
WB Predicted band size	Calculated MW: 19 kDa; Observed MW: 19 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Recombinant protein of human CIRBP
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Application
IP	1/20
WB	1/500-1/1000
IHC	1/50-1/100

	Western blot analysis of CIRBP in Hela lysates using CIRBP antibody.
	Immunohistochemistry analysis of paraffin-embedded Human breast cancer using CIRBP antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.