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瑞威尔生物科技 REVERE

Rabbit Monoclonal Antibody to CRM1

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别名:XPO1; CRM1; Exportin-1; Exp1; Chromosome region maintenance 1 protein homolog
应用:WB,IHC,ICC
反应种属:Human,Mouse,Rat
规格:50μl/100μl

Description
Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP). Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins.
Specification
Aliases XPO1; CRM1; Exportin-1; Exp1; Chromosome region maintenance 1 protein homolog
Entrez GeneID 7514
Swissprot O14980
WB Predicted band size Calculated MW: 123 kDa; Observed MW: 123 kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen A synthetic peptide of human CRM1
Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Application
WB 1/500-1/1000
IHC 1/50-1/100
ICC 1/50-1/200

Western blot analysis of CRM1 in 3T3 lysates using CRM1 antibody.

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。