Rabbit Monoclonal Antibody to Cyclin A2

包装: 1G|100G|500G|1KG|100KG

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别名:CCN1; CCNA
应用:WB,IHC,ICC,IP
反应种属:Human
规格：50μl/100μl

Description
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues Ted. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions.

Description

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues Ted. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions.

Specification
Aliases	CCN1; CCNA
Entrez GeneID	890
Swissprot	P20248
WB Predicted band size	Calculated MW: 49 kDa; Observed MW: 55 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Recombinant protein of human Cyclin A2
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Application
IP	1/20
WB	1/500-1/1000
IHC	1/50-1/100
ICC	1/50-1/200

	Western blot analysis of Cyclin A2 in Jurkat, Hela lysates using Cyclin A2 antibody.
	Immunocytochemistry analysis of Cyclin A2 (green) in hela using Cyclin A2 antibody,and DAPI(blue)
	Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Cyclin A2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.