Rabbit Monoclonal Antibody to DKC1

包装: 1G|100G|500G|1KG|100KG

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别名:DKC1; NOLA4; H/ACA ribonucleoprotein complex subunit 4; CBF5 homolog; Dyskerin; Nopp140-associated protein of 57 kDa; Nucleolar protein NAP57; Nucleolar protein family A member 4; snoRNP protein DKC1
应用:WB,IHC,ICC
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1.

Specification
Aliases	DKC1; NOLA4; H/ACA ribonucleoprotein complex subunit 4; CBF5 homolog; Dyskerin; Nopp140-associated protein of 57 kDa; Nucleolar protein NAP57; Nucleolar protein family A member 4; snoRNP protein DKC1
Entrez GeneID	1736
Swissprot	O60832
WB Predicted band size	Calculated MW: 58 kDa; Observed MW: 58 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	A synthetic peptide of human DKC1
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Application
WB	1/500-1/1000
IHC	1/50-1/100
ICC	1/50-1/200

	Western blot analysis of DKC1 in K562, C6, 3T3, Hela lysates using DKC1 antibody.
	Immunocytochemistry analysis of DKC1 (green) in K562 using DKC1 antibody,and DAPI(blue).
	Immunohistochemistry analysis of paraffin-embedded Human breast cancer tissue using DKC1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.