Rabbit Monoclonal Antibody to eIF5A

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别名:EIF-5A; EIF5A1; eIF5AI; Eukaryotic initiation factor 5A
应用:WB,IHC,IP
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis.

Description

mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis.

Specification
Aliases	EIF-5A; EIF5A1; eIF5AI; Eukaryotic initiation factor 5A
Entrez GeneID	1984
Swissprot	P63241
WB Predicted band size	Calculated MW: 17 kDa; Observed MW: 17 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	A synthetic peptide of human eIF5A
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Application
IP	1/20
WB	1/500-1/1000
IHC	1/50-1/100

	Western blot analysis of eIF5A in Jurkat lysates using eIF5A antibody.
	Western blot analysis of eIF5A in Jurkat, THP-1, C6, 3T3, Hela lysates using eIF5A antibody.
	Immunohistochemistry analysis of paraffin-embedded Human breast cancer using eIF5A antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.