Rabbit Monoclonal Antibody to ERCC1

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别名:ERCC1; DNA excision repair protein ERCC-1
应用:WB,ICC
反应种属:Human,Mouse
规格：50μl/100μl

Description
DNA repair systems operate in all living cells to manage a variety of DNA lesions. Nucleotide excision repair (NER) is implemented in cases where bulky helix-distorting lesions occur, such as those brought about by UV and certain chemicals. Research studies have shown that expression of ERCC1 is related to survival rate and response to chemotherapeutic drugs in several human cancers including non-small cell lung cancer (NSCLC).

Description

DNA repair systems operate in all living cells to manage a variety of DNA lesions. Nucleotide excision repair (NER) is implemented in cases where bulky helix-distorting lesions occur, such as those brought about by UV and certain chemicals. Research studies have shown that expression of ERCC1 is related to survival rate and response to chemotherapeutic drugs in several human cancers including non-small cell lung cancer (NSCLC).

Specification
Aliases	ERCC1; DNA excision repair protein ERCC-1
Entrez GeneID	2067
Swissprot	P07992
WB Predicted band size	Calculated MW: 33 kDa; Observed MW: 39 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	A synthetic peptide of human ERCC1
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Application
WB	1/500-1/1000
ICC	1/50-1/200

	Western blot analysis of ERCC1 in K562, 3T3, Hela lysates using ERCC1 antibody.
	Immunocytochemistry analysis of ERCC1(green) in Hela using ERCC1 antibody,and DAPI(blue)