Rabbit Monoclonal Antibody to FDPS

包装: 1G|100G|500G|1KG|100KG

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别名:FPS; FPPS; POROK9
应用:WB,IHC
反应种属:Human,Hamster
规格：50μl/100μl

Description
Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.

Description

Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.

Specification
Aliases	FPS; FPPS; POROK9
Entrez GeneID	2224
Swissprot	P14324
WB Predicted band size	Calculated MW: 48 kDa; Observed MW: 48 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Hamster
Immunogen	A synthetic peptide of human FDPS
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Application
WB	1/500-1/1000
IHC	1/50-1/100

	Western blot analysis of FDPS in CHO-K1 lysates using FDPS antibody.
	Immunohistochemistry analysis of paraffin-embedded Human lung cancer using FDPS antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.