中文 
别名:HMGB1; HMG1; High mobility group protein B1; High mobility group protein 1; HMG-1应用:WB,IHC
反应种属:Human,Mouse,Rat
规格：50μl/100μl
| Description |
|---|
| High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Evidence suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, members of the NFκB family, ATF-2 and c-Jun to activate transcription. |
| Specification | |
|---|---|
| Aliases | HMGB1; HMG1; High mobility group protein B1; High mobility group protein 1; HMG-1 |
| Entrez GeneID | 3146 |
| Swissprot | P09429 |
| WB Predicted band size | Calculated MW: 25 kDa; Observed MW: 25 kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | A synthetic peptide of human HMGB1 |
| Formulation | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Application | |
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
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Western blot analysis of HMGB1 in K562, rat Brain, C6, 3T3, Hela lysates using HMGB1 antibody. |
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Immunohistochemistry analysis of paraffin-embedded Human tonsil using HMGB1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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