Rabbit Monoclonal Antibody to Hydroxyl-Histone H2A (Tyr39)

包装: 1G|100G|500G|1KG|100KG

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别名:H2A.1; H2A/c; H2A1; H2AFC:; H2AFD; H2AFI; H2AFN; H2AFP; HIST1H2AG; HIST1H2AI; HIST1H2AK; HIST1H2AL; HIST1H2AM; histone cluster 1; H2ai; Histone H2A type 1; Histone H2A/p
应用:WB,IHC
反应种属:Human,Mouse
规格：50μl/100μl

Description
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Description

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Specification
Aliases	H2A.1; H2A/c; H2A1; H2AFC:; H2AFD; H2AFI; H2AFN; H2AFP; HIST1H2AG; HIST1H2AI; HIST1H2AK; HIST1H2AL; HIST1H2AM; histone cluster 1; H2ai; Histone H2A type 1; Histone H2A/p
Entrez GeneID	3012
Swissprot	P04908
WB Predicted band size	Calculated MW: 14 kDa; Observed MW: 14 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	A synthesized peptide derived from human Histone H2A (hydroxyl Y39)
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Application
WB	1/500-1/1000
IHC	1/50-1/100

	Western blot analysis of Hydroxyl-Histone H2A (Tyr39) in 3T3 lysates using Hydroxyl-Histone H2A (Tyr39) antibody.
	Western blot analysis of Hydroxyl-Histone H2A (Tyr39) in Hela, A549, HL-60 lysates using Hydroxyl-Histone H2A (Tyr39) antibody.Observed band size:14kDa.
	Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Hydroxyl-Histone H2A (Tyr39) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.